Company Overview
Powder Intelligence is a university spin-off startup
from Gifu Pharmaceutical University, leveraging expertise in pharmaceutics
and powder engineering to drive the development of novel formulations
and materials across the pharmaceutical, cosmetics, and food industries.
Philosophy
Solution by Powder Science
Powder behavior is a complex system governed by numerous interrelated factors—particle size,
shape, surface properties, specific surface area, moisture,
electrostatic charge, and even manufacturing history.
By integrating powder science with data analytics, Powder Intelligence provides
scientifically grounded solutions to challenges in powder processing.
Company Profile
| Company Name | Powder Intelligence Co., Ltd. |
|---|---|
| Location | 1-25-4 Daigaku-Nishi, Gifu, 501-1196, Japan (Inside Gifu Pharmaceutical University) |
| Established | July 7, 2025 |
| CEO | Yasuhiro Shimada |
| Business Activities |
|
Scientific Consultants
Yasuhiro Shimada, Ph.D. (Pharm. Sci.), Ph.D. (Eng.)
- Former CEO, Nanoseeds Co., Ltd.
- Technical Advisor, Marktec Corporation
- Visiting Scientist, Gifu Pharmaceutical University
Kohei Tahara, Ph.D. (Pharm. Sci.)
- Professor, Laboratory of Pharmaceutical Engineering, Gifu Pharmaceutical University
History
| 2019–2021 |
Selected for the “Knowledge Hub Aichi Priority Research Project Phase III”(Project: “Development of an AI-based prediction system for powder material properties”) A large-scale powder property database was constructed through industry–government–academia collaboration, and development of AI-based predictive systems was initiated. |
| July 2025 | Establishment of Powder Intelligence Co., Ltd. |
Services
Whatever the Powder, We have the Solution.
If your challenge involves powder, we are ready to help.
We are not limited to any specific measurement methodology. From fundamental
JIS-based testing to advanced rheological analysis—and even the development
of custom evaluation systems tailored to your manufacturing line—we leverage
every possible approach to derive the optimal solution for your powder processes.
1. Consulting & Integrated Solutions
Our experts in pharmaceutical manufacturing, powder engineering, and data science provide end-to-end support—from R&D to troubleshooting in production.
- Root cause analysis (troubleshooting)
- Raw material selection and equivalence evaluation
Physicochemical comparison and risk assessment when changing suppliers or materials - Materials informatics support
Utilizing the proprietary powder property database and expertise of Gifu Pharmaceutical University, we support the integration and analysis of your internal experimental data

2. Development & Prototyping of Powder Process Equipment
“If it doesn’t exist, we create it.”
We translate research needs into practical solutions.
- Development of analytical instruments for pharmaceutical powders
Designing novel systems to capture critical variables not measurable with conventional equipment - Process improvement and prototype development
Design and fabrication of custom units and fixtures to solve specific manufacturing issues (e.g., adhesion, poor flowability) - Next-generation formulation process technologies
Supporting equipment development for emerging technologies such as powder-based additive manufacturing (3D printing)

3. Interpretation & Re-evaluation of Powder Property Data
We do not simply measure—we derive the correct answer for manufacturing from your data.
-
Fundamental Properties & Morphological Analysis
Accurate characterization of powders as solid materials- Particle size distribution
- Particle morphology (SEM)
- Specific surface area
- True density
- Dynamic vapor sorption (DVS)
-
Compression & Mechanical Properties
Understanding the causes of tableting failures such as poor compaction and cracking- Compression behavior analysis (e.g., Heckel analysis)
- Granule and single-particle strength measurement
- Tableting tests and tablet property evaluation
-
Flowability, Adhesion & Powder Rheology
From hopper blockage to filling and mixing behavior—understanding how powders move- Comprehensive flowability evaluation
- Powder bed shear testing
- Dynamic flow and rheological analysis

Representative Publications
- Shimada, Y., Yonezawa, Y., Sunada, H. Measurement and evaluation of the adhesive force between particles by the direct separation method. Journal of Pharmaceutical Sciences. 2003;92(3):560–568.
- Shimada, Y., Hatano, S., Matsusaka, S. A new method for evaluating powder flowability using constant-volume shear tester. Advanced Powder Technology. 2018;29(12):3577–3583.
- Gotoh, A., Yamazoe, E., Ito, T., Koide, Y., Yamada, M., Shimada, Y., Tahara, K., 2024. Effects of excipient properties on pharmaceutical printlet fabrication via selective laser sintering 3D printing. Adv. Powder Technol. 35, 104678.
- Tadauchi, T., Yamada, D., Koide, Y., Yamada, M., Shimada, Y., Yamazoe, E., Ito, T., Tahara, K., 2022. Improving the powder properties of an active pharmaceutical ingredient (ethenzamide) with a silica nanoparticle coating for direct compaction into tablets. Powders 1, 231–242.